Medical microdosing refers to the clinically informed, safety-screened exploration of very low, sub-perceptual doses of a psychedelic substance (most commonly psilocybin or LSD) within a medical or research framework. Unlike recreational use, a “medical” lens emphasizes:

 

• screening + contraindications

• medication interaction awareness

• mental health history review

• informed consent + risk education

• integration support + monitoring

 

Because access to regulated psychedelic care is still limited in many places, it’s important to name this clearly: most microdosing happening today is not medical it’s  self-directed. That gap is exactly why education and harm reduction matter.

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Microdosing vs. Psychedelic Assisted Therapy

 

Microdosing is often discussed alongside “psychedelic medicine,” but in research and clinical settings, most therapeutic outcomes reported for psilocybin involve full-dose psychedelic-assisted therapy, not microdosing. For example, large clinical studies of psilocybin for depression have focused on supervised, higher-dose sessions in structured therapeutic environments. 

 

Microdosing, by contrast, is typically explored for subtle shifts in mood, focus, or emotional regulation yet the science is still emerging, and results are mixed.

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What we 

don’t

 know yet

 

Newer analyses and trials continue to question popular claims that microdosing reliably enhances mood, attention, or productivity, with some studies reporting null results in key areas. 

 

Mothers of the Mycelium stance: we hold microdosing as a community-education and harm-reduction conversation, not a guaranteed wellness “hack.”

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Microdosing and Medication Interactions

 

A medical framework takes medication interactions seriously, especially because classic psychedelics influence serotonin signaling pathways.

 

In clinical protocols and dosing papers, careful attention is given to contraindications and medication considerations often requiring a clinician to evaluate risk, mental health history, and current prescriptions. 

 

Important note: Do not stop or change prescribed medication to microdose without medical support.

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What “Medical” Means to Us at Mothers of the Mycelium

 

At MOM, “medical microdosing” means we center:

 

• education over persuasion

• safety over shortcuts

• postpartum-informed care

• nervous-system literacy

• trauma-aware community support

• referral to licensed professionals when needed

 

We also believe healing is not only biochemical it’s relational, embodied, and culturally held.

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Gentle Disclaimer

 

This page is for education only and does not provide medical advice, dosing guidance, diagnosis, or treatment. If you are pregnant, postpartum, breastfeeding, or taking prescription medication, consult a qualified clinician before considering any psychedelic substance.

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Breastfeeding & Maternal Safety

 

Human data on microdosing while breastfeeding remains limited, and there is currently no conclusive research establishing safety for nursing infants. Because of this gap, most medical and research institutions urge heightened caution during the postpartum and breastfeeding period, recognizing it as a uniquely sensitive window for both mother and baby.

 

At Mothers of the Mycelium, we believe the absence of data does not equal the absence of lived experience. Many mothers are already navigating questions around microdosing, mental health, nervous system regulation, and postpartum recovery often without adequate guidance or culturally responsive care.

 

To responsibly address this gap, Mothers of the Mycelium is actively working to expand community-centered data through our evaluation (Ivalu) program, which centers:

 

• postpartum and breastfeeding experiences

• maternal mental health outcomes

• nervous system regulation and emotional well-being

• harm-reduction education and informed consent

• non-extractive, mother-led research practices

 

Our approach prioritizes maternal safety, informed choice, and ethical data collection, while honoring the wisdom of mothers’ lived experiences alongside emerging science.

 

Until more conclusive research is available, we encourage mothers who are breastfeeding to move slowly, seek professional guidance, and engage in community-based education before making any decisions involving microdosing.