How a Single Psilocybin Dose Can Change Your Brain (Latest Research)

Explore the latest science on what psilocybin does to your brain. This overview explains how the compound can quiet the brain's "inner narrator" (the default mode network), forge new neural connections, and open a temporary window of heightened brain flexibility. The video also covers the current state of clinical trials for treatment-resistant depression and where psilocybin stands on the path to becoming a potential medical treatment.

Reference Letheby, Chris, and Philip Gerrans. “Self unbound: ego dissolution in psychedelic experience.” Neuroscience of consciousness vol. 2017,1 nix016. 30 Jun. 2017, doi:10.1093/nc/nix016

Chapters

0:00 – Can the brain reboot?

0:21 – How psilocybin works

1:51 – The brain’s “default mode” quiets

2:29 – New brain connections form

3:08 – The “fresh snow” effect

3:33 – Enhanced plasticity window

4:39 – How perception shifts

5:21 – Integration after treatment

6:06 – Where trials stand now

7:41 – State programs & access

8:30 – New research directions

8:50 – What to know before trying

9:51 – Why guidance matters

10:38 – Big picture summary

Disclaimer: All of the information on this channel is for educational purposes and not intended to be specific/personal medical advice from me to you. Watching the videos or getting answers to comments/question, does not establish a doctor-patient relationship. If you have your own doctor, perhaps these videos can help prepare you for your discussion with your doctor.